The series follows an older Peter Parker who becomes Spider-Man for the first time later in life, already a father of two children (Richard and May) and married to Mary Jane "MJ" Watson-Parker, as opposed to his early/late teens like in the mainline.

The series is part of the new Ultimate Universe timeline of Earth-6160, which puts several Marvel characters in a radically altered sociopolitical status quo, including elements of alternate history.

[3] Although Harry Osborn keeps the Green Goblin identity in the new continuity, he is reimagined as a superhero, closer to the classic portrayal of Iron Man.

[4] Following the "Ultimate Invasion" plotline, Peter Parker is a married man living in New York City with his wife Mary Jane "MJ" Watson and his two children Richard and May.

Later, Peter reveals his identity as Spider-Man to armored vigilante, the "Green Goblin", who unmasks to show himself as Harry Osborn.

J. Jonah Jameson and Ben Parker launch "The Paper" including their investigation into the different crimes being stopped by Spider-Man and Green Goblin while using former co-worker Robbie Robertson as their inside person.

After brainwashing some people at the bank into attacking Spider-Man, Mister Negative tells Wilson Fisk and his fellow lieutenants about it as Black Cat recuperates in a wheelchair.

Below Staten Island, Mole Man learns from Kraven the Hunter that he has Peter and Harry in his clutches where he will have his great hunt on them in Subterranea which is now filled with dinosaurs and other strange creatures.

Kraven the Hunter takes them back to the surface to see Peter and Harry who have bomb collars on them and feeding them their last meal before the hunt.

[7] Murdock was present at the memorial for the victims of a terrorist attack on the city of New York, speaking to those affected before relinquishing his position to Harry Osborn to deliver a speech of his own.

[9] User comments in social media praised the arts and plots, and compared it favourably to the main Spider-Man comics.