When the theme first launched in 2002, it was inspired by the Spider-Man film released the same year and was part of the Lego Studios line.

Additional sets were released two years later, based on the film's sequel, Spider-Man 2.

[2][3] The theme was discontinued before the release of Spider-Man 3, and the rights were sold to rival Mega Brands, who entered a multi-year licensing deal with Marvel Enterprises, giving them the rights to produce playsets, vehicles, and other building-themed products based upon various Marvel characters for their Mega Bloks toys.

[4] In 2012, Lego revived the theme, starting with several waves of sets based on the Ultimate Spider-Man animated series in their Marvel Super Heroes line.

The product line focuses on Spider-Man battling against super villains in New York City.

While sometimes recreating events from storylines, the sets are most often playsets with no connection to any sense of timeline previously established in the Marvel Universe.

They are 76036 Carnage's Shield Sky Attack, and 76037 Rhino and Sandman Super Villain Team-up.

In 2014, the polybag 5002125 Electro was released as a promotion, based on The Amazing Spider-Man 2 film.

It is currently the tallest of all licensed and unlicensed modular sets, measuring roughly 82 centimeters and is composed of 3772 bricks and pieces.

The Daily Bugle Skyscraper comprises four stories (not including the roof), a newspaper stand, a "Spider-Buggy", and a taxi.

[25][26] A fourth set, 76261 Spider-Man Final Battle, was announced in May 2023 for an August release.

[27] 76261 includes the first minifigs based on Tobey Maguire's Spider-Man and Alfred Molina's Doc Ock manufactured since 2004, the first minifig of Willem Dafoe's Green Goblin since 2003, the second overall minifigs of Andrew Garfield's Spider-Man and Jamie Foxx's Electro since 2014, and the first overall appearance of Thomas Hayden Church's Sandman in LEGO form, represented by a buildable sand hand.

[8] Produced as an exclusive for San Diego Comic-Con 2020, Classic Suit Miles Morales was released as part of a sweepstakes in October 2020, based on the Spider-Man: Miles Morales video game by Insomniac Games.

The accompanying soundtrack includes interviews with Marvel Senior Editors Tom Brevoort and Nick Lowe.

It is a re-imagined retelling of Avengers: Age of Ultron while using some elements from Ant-Man and Spider-Man.

In the film, LEGO Peter is working for J. Jonah Jameson at the Daily Bugle.

The Spot suddenly appears in his universe and he then immediately contacts and alerts Miguel O'Hara / Spider-Man 2099 about the circumstance and is later assigned by Jess Drew / Spider-Woman to a team to aid in dealing with the Spot situation.

The sequence was animated by the 14-year-old Preston Mutanga, who attracted attention from the filmmakers after he published a re-animated version of the movie's trailer in a Lego style, which he made in Blender.