The Umpqua River (/ˈʌmpkwə/ UMP-kwə) on the Pacific coast of Oregon in the United States is approximately 111 miles (179 km) long.

From its source northeast of Roseburg, the Umpqua flows northwest through the Oregon Coast Range and empties into the Pacific at Winchester Bay.

The "Hundred Valleys of the Umpqua" form the heart of the timber industry of southern Oregon, generally centered on Roseburg.

The North Umpqua rises from snowmelt and is considered one of the premier summer steelhead streams in the West.

At Elkton, it turns to flow west through a narrower canyon past Scottsburg, which is located at the head of tide.

The Umpqua is one of four major rivers in Oregon that start in or east of the Cascade Range and reach the Pacific Ocean.

Next come Bottle, Cougar, Wolf, Powell, Leonard, Basin, and Lost creeks followed by Galagher Canyon.