United Nations station was opened to the public on December 1, 1984, as part of LRT's inaugural southern section, known as the Taft Line.

[1][2] United Nations station is also near educational institutions such as the Technological University of the Philippines, the Philippine Normal University, Adamson University, Santa Isabel College Manila, Emilio Aguinaldo College, Araullo High School and Manila Science High School.

It is also adjacent to the interconnecting Times Plaza, World Health Organization Western Pacific Region office, National Bureau of Investigation headquarters, Medical Center Manila, Manila Doctors Hospital and Waterfront Manila Pavilion Hotel and Casino.

United Nations station is served by buses, jeepneys, and UV Express along Taft Avenue and other nearby routes.

Regular taxis, cycle rickshaws, tricycles, and e-tricycles also stop at and near the station.