The institute was moved to the present campus in North Okkalapa on 25 September 1996 and is now situated approximately 12 miles (19 km) from downtown Yangon.

Postgraduate studies for master's degrees in Anatomy and Physiology started in 1973.

The University of Medicine 2, Yangon is one of the most selective schools in the nation as the medical schools continue to be the top choice amongst top students in Myanmar.The students who want the admission to this school must make sure that they are in top 0.02% of the total exam candidates in college entrance exam of the year.

Students attend lectures & clinics in Medicine, Surgery, Child Health, Obstetrics & gynecology, and are posted to the various teaching hospitals, including Urban Health facilities as part of Preventive and Social Medicine teaching.

After each posting, students must take multiple choice questions of each subjects.

In Bloc- posting, students are trained intensively in major speciality through lectures, seminars, presentation, clinical and theory integration and with real patients.

Each posting lasts for 3 months and at the end of each posting, students have to take completion tests which composed as written and bedside exam with real patients.

Written exam lasts for 8 days because each subject has 2 paper of questions as follows.

All students, after successful completion of the Final Part II examination, are continued to train hands-on for a period of one year as house surgeons in the recognized Teaching Hospitals in Yangon.

Before 1997, the degree was conferred upon completion of the second part of the final year.