1102322326ENSG00000148704ENSMUSG00000006270Q5SQQ9Q2NKI2NM_199131NM_001112704NM_009501NP_001106175NP_954582NP_033527Ventral anterior homeobox 1 is a protein that in humans is encoded by the VAX1 gene.

It is also present in mice and xenopus frogs, which suggests a long evolutionary history, and in those organisms its expression is confined to the forebrain, optic and olfactory areas.

[8] VAX1 gene is a transcription factor that has a homeodomain located in the 100-159 amino acid position and an Ala–rich region located in 216-253 amino acid position of the gene.

[8][9][10] Mice with homozygous VAX1 mutations have been reported to display craniofacial malformations including cleft palate.

[12][13] Replication studies have confirmed these associations in different population groups[14][15]