She received her Ph.D. from the University of California, San Francisco, advised by Irwin Kuntz and Peter Kollman, and subsequently held a postdoctoral position at Stanford University with Michael Levitt, a co-recipient of the 2013 Nobel Prize in Chemistry.
[1] As of 2021, she is also the chief executive officer of AltPep, a biomedical startup that was a spinoff from her research at the University of Washington.
Daggett is well known for large-scale simulations of protein folding, especially unfolding, and native state dynamics through her "dynameomics" project.
[3][4] In 2005, the Daggett laboratory was awarded a supercomputing grant by the U.S. Department of Energy, which was renewed for almost two million processor-hours in 2006;[5] the group has also participated in Microsoft Research high-performance computing projects.
[7] Daggett was one of two University of Washington scientists named 2015 American Institute for Medical and Biological Engineering fellows.