[4] Van Cleef & Arpels opened boutiques in holiday resorts such as Deauville, Vichy, Le Touquet, Nice, and Monte-Carlo.

In 1925, a Van Cleef & Arpels bracelet with red and white roses fashioned from rubies and diamonds won the grand prize at the International Exposition of Modern Industrial and Decorative Arts.

A significant challenge in creating the crown was that all the precious stones had to be selected from the Imperial Treasury of Iran, and none of the gems could leave the country, so the work had to be done there.

Standalone boutiques are present in Geneva, Zürich, Vienna, Munich, London, Milan, Shanghai and Paris, where the company has multiple locations, including its flagship store at Place Vendôme.

In the United States, the company operates standalone boutiques in Boston, Dallas, Las Vegas, Manhasset, Naples, Palm Beach, San Francisco, Bal Harbour, Chicago, Houston, McLean, King of Prussia, Short Hills, Aspen, Beverly Hills, Costa Mesa and Miami alongside their New York City flagship store, which was redesigned in 2013.

[16] A 1936 Van Cleef & Arpels custom jewelry piece with a "Mystery Setting" sold for $326,500 during an auction at Christie's New York in 2009.