[2] It is a normal part of the oral flora but can be associated with diseases such as periodontitis and dental caries as well as various systemic infections, including meningitis and osteomyelitis.

[3] It has also been isolated from women with bacterial vaginosis and has been associated with hypertension together with Campylobacter rectus and Prevotella melaninogenica.

[5] Specifically, Streptococcus mutans and V. parvula can form multispecies biofilms that lead to a lower susceptibility to antimicrobial treatments, resulting in periodontitis and dental caries.

[6] V. parvula bacteria are susceptible to and typically treated with metronidazole and penicillin in clinical reports.

[7][8][9][10] Other antibiotics that have been shown to be active against V. parvula include cephalosporin, clindamycin, and chloramphenicol.