The highest mountain in the Palatinate, the Donnersberg, rises some 30 km away to the south-southwest (as the crow flies).

Vendersheim is surrounded by vineyards shaped like a horseshoe with the open end towards the south, and has more than 1,500 hours of sunshine each year.

After the last ice age and the return of plant life began the permanent settlement of the Rhine valley by the Linear Pottery culture.

Vendersheim was among the places that became simultanea, that is, Catholic, Lutheran and Reformed citizens were and would remain entitled to their right of abode.

During the occupation by French troops from 1792 to 1814, Vendersheim belonged to the Department of Mont-Tonnerre (or Donnersberg in German).

Feudal rights were abolished and for births, marriages and deaths, only state certification was valid.

A different coat of arms was proposed for Vendersheim in 1956, but never adopted, containing only the charges and tinctures seen below the line of partition.