Victoria Hospital for Sick Children is a building in Toronto, Ontario, Canada.

The building has received a Commendation of Adaptive Re-use from the Toronto Historical Board.

The construction of the five-storey building was a very important step in the history of the hospital since it was previously located in a small downtown house which was rented for sixteen years by Elizabeth McMaster, the founder of the hospital, with support from a group of Toronto women (Toronto Archives).

The invention of pablum, the introduction of incorporated X-rays in 1896, and the origins of the battle for compulsory milk pasteurization in 1908 occurred in this building (Adams 206).

It is located at the corner of College and Elizabeth Streets, near the Toronto General Hospital.