In 2014, Pande co-founded Globavir Biosciences, an infectious disease startup addressing antibiotic resistance threats in developed countries as well as needs in viral infections around the world, including Ebola and dengue fever.

The lab brings together researchers from many departments, including chemistry, computer science, structural biology, physics, biophysics, and biochemistry.

[14] Pande directed the now-defunct Genome@home project with the goal to understand the nature of genes and proteins by virtually designing new forms of them.

[15][16] Some of the programs and libraries involved are free software with GPL, LGPL, and BSD licenses, but the Folding@home client and core remain proprietary.

[2] While in high school, Pande won fourth place in the 1988 Westinghouse Science Talent Search for a computer simulation of a space-based ballistic missile defense.

[21] After graduating from high school in 1988, Pande worked briefly at the video game development company Naughty Dog in the early 1990s while in his late teens, serving as a programmer and designer on their 1991 release Rings of Power.

[22][23] While Pande was attending MIT and Naughty Dog was based in Boston, he portrayed the secret boss character in the 3DO fighting game Way of the Warrior.

[2][25] In 2015, Pande received the DeLano Award for Computational Biosciences, as well as the Camille and Henry Dreyfus Distinguished Chair in Chemistry.