In enzymology, a vinylacetyl-CoA Delta-isomerase (EC 5.3.3.3) is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, vinylacetyl-CoA, and one product, crotonyl-CoA.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds.
The systematic name of this enzyme class is vinylacetyl-CoA Delta3-Delta2-isomerase.
Other names in common use include vinylacetyl coenzyme A Delta-isomerase, vinylacetyl coenzyme A isomerase, and Delta3-cis-Delta2-trans-enoyl-CoA isomerase.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U8V.