The Virgin and Child with the Infant Saint John the Baptist is a tempera painting on wood executed by the Italian Renaissance master Sandro Botticelli and his studio (Bartolomeo di Giovanni or Raffaelino di'Carli).

Its origin goes back to the hieratic representations of the High Middle Ages where Mary, crowned, enthroned or standing, presents the divine infant in her arms.

We emphasize the beautiful structure of the composition, in which the figures of the Virgin and Child stand boldly inside the tondo, hereby freeing himself from the elegant symmetry of his youth.

It is equally noteworthy the remarkable intensification of the emotional bond that unites Mary and baby Jesus, unusual in Madonnas executed by the painter in his youth.

Antonino Santangelo emits a similar opinion, noting that the "free and harmonious intertwining of hands and faces, mobility and precision recall the works of Botticelli shortly before 1500".

Roberto Longhi believes that the drawings of the landscape and the Infant Saint John the Baptist are more typical of Ghirlandaio and proposes the name of Bartolomeo di Giovanni – disciple of both painters – as a possible contributor to the implementation of the Botticelli tondo.