The commune territory is bounded by the comuni of Buccheri, Francofonte, Giarratana, Licodia Eubea, Militello in Val di Catania, Mineo.

[3] The modern town developed in the Middle Ages around a now non-extant castle,[4] as a fief of various lords, including the Chiaromontes and the Schittinos, although for many years it was also part of the royal domain.

The portal on the left flank of the church, in splendid 15th-century Gothic-Catalan style, probably derived from the old Town Hall, destroyed by the earthquake in 1693; in the interior there are late 18th century stuccos and a wooden ceiling by Natale Bonaiuto, as well as two paintings (The Martyrdom of St. Laurence and the Madonna delle Mercede) by Filippo Paladini (or Paladino), born in Florence about 1544.

The front of the church of Santa Teresa is said to be the setting for scenes from Cavalleria Rusticana, the libretto of which is based on the play of the same name by Giovanni Verga, who lived in Vizzini for a time.

The writer Giovanni Verga used Vizzini as the setting for his Cavalleria Rusticana and Mastro Don Gesualdo, describing places and scenes that are still recognizable (the prickly pears of Cunziria, and in a sloping alley the house of the Trao family).