Vonitsa (Greek: Βόνιτσα) is a town in the northwestern part of Aetolia-Acarnania in Greece, seat of the municipality of Aktio-Vonitsa.

The beach town is situated on the south coast of the Ambracian Gulf, and is dominated by a Venetian fortress on a hill.

Vonitsa is built near the site of ancient Anactorium, an important city of Acarnania, founded by the Corinthians in 630 BC.

After the Greek War of Independence, the town became a part of the Kingdom of Greece in 1832.

On 18 October 1862 the insurrection that later spread to Athens and lead to the overthrow of King Otto of Greece, started in Vonitsa.