These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

It may be involved in breast cancer, and its protein signaling is, it is presumed, a molecular switch that governs adipogenesis.

Gain-of-function of Wnt10b in mouse hearts has shown to improve cardiac tissue repair after myocardial injury, by promoting coronary vessel formation and attenuating pathological fibrosis.

This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.

This article on a gene on human chromosome 12 is a stub.