The two stations share studios on Ledgeview Drive in Westbrook; WPXT's transmitter is located in West Baldwin, Maine.

On October 7, 2001, WPXT switched to The WB; the deal, which also included WDBD in Jackson, Mississippi, came after renewal negotiations between Fox and Pegasus broke down.

A Fox spokesman said that the two stations "were not honoring the terms and conditions of the affiliate agreement," an assertion denied by WPXT staff.

[4][5] Pegasus declared bankruptcy in June 2004 over a dispute with DirecTV (then co-owned with Fox by News Corporation) over marketing of the direct broadcast satellite service in rural areas.

The Pegasus station group was sold in August 2006 to private investment firm CP Media, LLC of Wilkes-Barre, Pennsylvania, for $55.5 million.

On January 24, 2006, Time Warner and CBS Corporation announced that they would merge the broadcast operations of The WB and UPN to form The CW Television Network.

WPXT ceased analog transmission August 12, 2008, more than seven months prior to the original Federal Communications Commission (FCC) digital switchover deadline of February 17, 2009, due to transmitter failure.

[12][13] Hearst Television announced its acquisition of WPXT on July 30, 2018; the $3,350,000 purchase created a duopoly with ABC affiliate WMTW (channel 8).

WPXT even produced a weeknight broadcast at 7 on that station at one point but the show was eventually canceled due to poor ratings and inconsistent viewership.

It made national headlines a week before the 2000 Presidential election when reporter Erin Fehlau (now at ABC affiliate WMUR-TV) revealed Republican candidate George W. Bush had been convicted for driving under the influence of alcohol 24 years earlier.

On October 31, 2011, WPXT and WCSH established another news share agreement and debuted an hour-long extension of the big three outlet's weekday morning show.

[21] Following WPXT's sale to Hearst Television, the station announced that a WMTW-produced prime time newscast would premiere on September 24, 2018.