He studied in Vienna, working as a demonstrator of physiology under Sigmund Exner and pathology under Anton Weichselbaum.
He received his doctorate from the University of Vienna in 1912, and worked as a bacteriologist in the Bulgarian Army during the First Balkan War in the same year.
He trained in pathology under Weichselbaum, and was a Medizinaloffizier in charge of a medical laboratory in the Austro-Hungarian Army during World War I, serving in Bosnia, Russia, Turkey and Palestine.
From 1921 to 1936 he was Director of Laboratories at the second Gynaecological Clinic of the University of Vienna, where he carried out studies on cervical cancer and developed his eponymous test.
In 1937 he emigrated to the United States with his wife and two daughters due to the threat of Nazism, working initially at the Jewish Memorial Hospital in New York City.