Wanseko is located on the eastern shores of Lake Albert, in Buliisa District.

It lies approximately 15 kilometres (9.3 mi), by road, north of the district headquarters at Buliisa.

[1] This is about 104 kilometres (65 mi), by road, north of Hoima, the nearest large city.

[2] Wanseko is approximately 301 kilometres (187 mi), by road, northwest of Kampala, Uganda's capital and largest city.

[3] The settlement lies at the mouth of the Victoria Nile, at it enters Lake Albert.