Wanyange Girls School is a girls' boarding government-aided secondary school on Nyange hill in Jinja District of the Eastern Region, Uganda.

When Wanyange Girls School opened on 1 March 1960, it was temporarily located at Buckley High School in Iganga.

In 1967, it was provisionally merged with Busoga College Mwiri whilst keeping its own location on Nyange hill, but having the name Busoga College Wanyanga.

[2][3] In 2016, Schoolnet Uganda rated Wanyange Girls School as the tenth best girls' school in Uganda.

[4] In 2018, the first RCMRD Uganda Space Challenge was held at Wanyange Girls School after two RCMRD Space Challenges had been held in Kenya in 2017 and 2018.