The first volume of Web of Spider-Man published by Marvel Comics for 129 issues, cover dated from April 1985 to October 1995.

[2] The series was launched with an April 1985 cover dated issue by writer Louise Simonson and penciller Greg LaRocque[3] and featured the return of Spider-Man's alien black costume, which attempted to rebond with Peter Parker.

The costume could nullify Spider-Man's spider-sense, and this was the first clue of a puzzle that Michelinie was planning to weave to introduce Venom.

[9] The "Tribute-to-Teen-Agers" story in issue #35 saw the debut of the creative team of writer Gerry Conway and artist Alex Saviuk.

[10][11] Web of Spider-Man #50 featured guest-appearances by several minor Marvel super-heroes such as the Puma, the Prowler, and Rocket Racer.