Woodford County is part of the Lexington-Fayette, KY Metropolitan Statistical Area.

[7] Queen Elizabeth II stayed in Woodford County at Lane's End Farm in May 2007.

21.00% of all households were made up of individuals, and 7.50% had someone living alone who was 65 years of age or older.

Woodford County is home to one of Kentucky's oldest bourbon whiskey distilleries, Labrot & Graham (established 1812, now owned by Brown–Forman, which produces the Woodford Reserve brand); the Life Adventure Center, an equine and outdoor experience to assist youth affected by trauma;[18] and the Kentucky Castle.

Since 1956, Woodford County has generally voted Republican at the federal level.

However, it sometimes votes for Democrats statewide, which it did for Andy Beshear in the 2019 and 2023 gubernatorial elections.

The county voted "No" on 2022 Kentucky Amendment 2, an anti-abortion ballot measure, by 61% to 39%, and backed Donald Trump with 55% of the vote to Joe Biden's 43% in the 2020 presidential election.