Due to the establishment of modern infrastructure, including a far-distance road, the area around Wuqro Cherqos evolved into a town by itself, thus separated from Dongolo and became an economic and administrative centre by itself.

David Buxton lists the many ways Wukro "has been variously spelt: Agroo, Corou, Oucro, Ouquo, Ucro, Ouaqero, Oukero, Ouogro, Uogro, Woghuro, Wogro, Waqro, and Weqro.

[7] The place is part of the ancient trade route (particularly for salt) linking the Red Sea with inner Ethiopia, all the way to Lasta.

"[9] The next important European visit was in 1868 when Lieutenant-General Sir Robert Napier passed through the village on his way to Magdela where he defeated the Ethiopian Emperor Tewodros II.

During the Italian occupation, in 1938, there were shops and a hotel-restaurant, a car service station, a telephone and telegraph office and a health post.

[13] Wukro was used as his headquarters by Blatta Haile Mariam Redda during the Woyane rebellion, until Ras Abebe Aregai captured the town 17 October 1943.

[14] Dawit W. Girgis reports in his memoirs that in 1964, with the permission of Emperor Haile Selassie, the Israelis operated a secret base outside Wukro where members of the Anyanya (a Sudanese rebel group) were trained in guerrilla warfare.

It was bombed in mid-November 2020, then shelled by artillery fire a few weeks later, resulting in heavy destruction of property and multiple civilian deaths.

[19] Small towns in sub-Saharan Africa, such as Wukro, represent over half the urban population and offer an important space for women’s empowerment and advancement in between the confines in rural life and the anonymity of migrating to large cities.

[2] Women entrepreneurs in Wukro are for example owners of coffee shops (bunabéts) or traditional beer houses (inda siwa) that often combine making basic food (i.e. injera or grocery), or hair salon businesses.

[2] Previous population figures include: Wukro has been growing rapidly and building construction has increased pressure on scarce water resources.

The project had financial support from the National ONEWASH programme, UNICEF and UK Foreign, Commonwealth & Development Office, as well as the Tigray regional and national governments, Inaugurated in 2018, this included the development of more productive and reliable boreholes with a planning period from 2015 to 2035, designed to provide water equally over all water demand nodes of the distribution network.