Yaviza is a town and corregimiento in Pinogana District, Darién Province, Panama with a population of 4,441 as of 2010.

The nearest town on the river route is El Real de Santa María, which is the capital of Pinogana District.

The town was founded by Spanish missionaries as San Jerónimo de Yaviza in September 1638.

[5] As the Pan-American Highway was constructed, it eventually reached Yaviza as a dirt road.

But plans to complete the road to Colombia were stopped, leaving Yaviza as the end point of the northern half of the highway.