[2] People with this disease lack the capability to fight infections, and it is fatal if untreated.

Children with this condition typically present with infections and skin rashes.

[3] Unlike many forms of SCID, absolute lymphocyte count is normal and thymus is present.

[citation needed] ZAP70 deficiency SCID is caused by a mutation is the ZAP70 gene, which is involved in the development of T cells.

[3] Hematopoietic stem cell transplantation is the only known cure for ZAP70 deficient SCID.