The protein recruits histone modification enzymes to chromatin to affect gene activation.

[8] Zinc finger and BTB domain-containing protein 32 is also known as: Zbtb32 has been shown to interact with: The expression of ZBTB32 is induced by inflammatory cytokines and promotes proliferation of natural killer cells.

[15] ZBTB32 is highly expressed in spermatogonial stem cells, in hematopoietic stem and progenitor cells, in diffuse large B-cell lymphoma (DLBCL) and appears to suppress the immune system by silencing the CIITA gene.

Down-regulation of GATA3 expression and activity by the Zinc-finger elbow-related proline domain protein 2 (Zpo2), whereas Zbtb32 facilitates Zpo2 targeting to the GATA3 promoter, results in the development of aggressive breast cancers.

[18] This article incorporates text from the United States National Library of Medicine, which is in the public domain.