[3][4] After two seasons with Penn State where he played a combined 9 games, and had 14 tackles, he transferred to Texas Tech.

[13] In Week 1 of the 2022 season, McPhearson was named NFC Special Teams Player of the Week, after he made 2 special teams tackles and recovered a surprise onside kick attempt in a 38–35 win over the Detroit Lions.

During a preseason game against Cleveland in 2023, McPhearson suffered a torn Achilles which ended his season.

His father, Gerrick, earned a tryout for the New England Patriots as a defensive back in 1988, and his mother, Kim, played in the National Women's Football League.

His older brother Derrick played football at the University of Illinois, then spend some time with the Milwaukee Brewers organization.

Matthew was a 4th round draft pick out of high school to the Arizona Diamondback organization.