1,4-Dichloro-2-nitrobenzene is an organic compound with the formula C6H3Cl2NO2.

One of several isomers of dichloronitrobenzene, it is a yellow solid that is insoluble in water.

It is produced by nitration of 1,4-dichlorobenzene.

It is a precursor to many derivatives of commercial interest.

Nucleophiles displace the chloride adjacent to the nitro group: ammonia gives the aniline derivative, aqueous base gives the phenol derivative, and methoxide gives the anisole derivative.