2,4,6-Trichlorobenzoyl chloride

2,4,6-Trichlorobenzoyl chloride or Yamaguchi's reagent is an chlorinated aromatic compound that is commonly used in a variety of organic syntheses.

[2][3] It is the primary reactant in Yamaguchi esterification.

2,4,6-Trichlorobenzoyl chloride is prepared by reacting 2,4,6-trichloroaniline with n-butyllithium in a carbon dioxide atmosphere.

[4] Since 2,4,6-trichlorobenzoic acid is produced as a by product of the Yamaguchi esterification process, it can be refluxed again to recreate 2,4,6-trichlorobenzoyl chloride.

This article about an organic halide is a stub.

NFPA 704 four-colored diamond Health 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gas Flammability 0: Will not burn. E.g. water Instability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogen Special hazards (white): no code