The 2010 Copa Telmex was a men's tennis tournament played on outdoor clay courts.

Juan Carlos Ferrero won the singles title.

The singles line up was led by 2007 Copa Telmex champion and 2009 Copa Telmex runner-up Juan Mónaco, David Ferrer, Nicolás Almagro and Juan Carlos Ferrero.

other players were 2008 champion David Nalbandian, Richard Gasquet, Igor Andreev, Albert Montañés.

Juan Carlos Ferrero defeated David Ferrer 5–7, 6–4, 6–3 Sebastián Prieto / Horacio Zeballos defeated Simon Greul / Peter Luczak, 7–6(7–4), 6–3 The following players received wildcards into the main draw: The following players received entry from the qualifying draw: The following players received Special Exempts into the main draw: