The top three teams in the tournament qualified for the 2011–12 CONCACAF Champions League.
The away goals rule would be applied, and extra time and penalty shootout would be used to decide the winner if necessary.
The defending champion, Puerto Rico Islanders, received a bye to the second round.
However, it was announced on May 12, 2011, that Guyana's Alpha United, one of the semifinalists, would host the final round at Providence Stadium in Providence, Guyana, with the semifinals on May 25, and the third-placed match and the final on May 27.
Puerto Rico Islanders, Tempête, and Alpha United qualified for the Preliminary Round of the 2011–12 CONCACAF Champions League.