The 2012 African Women's Handball Champions League was the 34th edition, organized by the African Handball Confederation, under the auspices of the International Handball Federation, the handball sport governing body.

The tournament was held from November 16–24 in Tangier, Morocco, contested by 11 teams and won by Atlético Petróleos de Luanda of Angola.

Africa Sports National Olympic Club Primeiro de Agosto

Saltigue HC ABO Sport FAP Yaoundé HC Héritage Nairobi Water Petro Atlético [2] * Note:   Advance to quarter-finals   Relegated to 9th place classification

* Note:   Advance to quarter-finals   Relegated to 9th place classification