The 2018 African Women's Handball Champions League was the 40th edition, organized by the African Handball Confederation, under the auspices of the International Handball Federation, the handball sport governing body.

The tournament was held from October 19–28, 2018 in Abidjan, Ivory Coast, contested by 9 teams and won by Clube Desportivo Primeiro de Agosto of Angola.

[1] [2] ABO Sport Bandama Dynamique HC Héritage Petro Atlético Africa Sports FAP Yaoundé HC Vainqueur Primeiro de Agosto [3] * Note:   Advance to quarter-finals * Note:   Advance to quarter-finals [4]