[2] The draw of the tournament was held on 22 December 2015, 20:30 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay.
The teams were seeded based on their CONMEBOL ranking (shown in parentheses).
If still tied, extra time would not be played, and the penalty shoot-out would be used to determine the winner (Regulations Article 5.2).
Tied 2–2 on aggregate, Huracán won on away goals and advanced to the second stage (Group 4).
Tied 2–2 on aggregate, Independiente del Valle won on away goals and advanced to the second stage (Group 5).