The 2018 season was the New Orleans Saints' 52nd in the National Football League (NFL), their 43rd at the Mercedes-Benz Superdome and their 12th under head coach Sean Payton.

They swept their division rivals, the Atlanta Falcons, after a 31–17 victory on Thanksgiving night for the first time since 2015 while extending their second longest winning streak in franchise history to 10 games,[2] which came to an end when the Saints lost to the Dallas Cowboys 13–10, on November 29.

After a Week 16 win over the Pittsburgh Steelers, the Saints clinched home field advantage throughout the playoffs for the first time since 2009.

In the playoffs, the Saints defeated the defending Super Bowl champion Philadelphia Eagles 20–14 in the Divisional Round.

This game was one year removed from last season, where the Saints overcame a 15-point deficit against the Redskins at home with three minutes remaining.

Drew Brees would throw his 500th touchdown pass against Baltimore and becoming the third quarterback in modern NFL history to defeat all 32 teams playing in the 2018 season – after Peyton Manning and Brett Favre.

The Saints travelled to Minnesota for the first time since the 2017 Divisional round; during which safety Marcus Williams missed a tackle on the game's final play that allowed a 61-yard game-winning touchdown reception by Stefon Diggs.

In this divisional round rematch, despite a good offensive showing from Kirk Cousins and Stefon Diggs, and Drew Brees who was held to just 120 passing yards, New Orleans still won the game 30-20 to go to 6-1 and avenge their aforementioned playoff loss.

Star wide receiver Michael Thomas, after scoring on his 12th reception, paid homage to former Saints wide receiver Joe Horn; while simultaneously taunting former teammate Brandin Cooks and the Rams by pulling out a cell phone from underneath the goalpost pretending to imitate making a phone call.

After losing the newly acquired Dez Bryant for the year with an Achilles' tear in practice, several players, including Michael Thomas, and running backs Mark Ingram II and Alvin Kamara paid tribute by throwing up Bryant's signature 'X' celebration each time they scored.

During the punt, Thomas Morstead was tripped up by the defender, prompting the Saints to get a free first down from the Roughing the Kicker penalty.

Late in the first half of the Week 5, Monday Night game against the Washington Redskins, Quarterback Drew Brees surpassed Brett Favre (71,838) and Peyton Manning (71,940) for the most career passing yards.

Marshon Lattimore stuns the Eagles with an interception to secure the Saints' victory and advance to the NFC Championship.

Coming off with the Divisional Round victory over the Eagles, the Saints remain in the Superdome to host the Los Angeles Rams.

The game was marred with controversy after the referees missed a pass interference call of Nickell Robey-Coleman's hit on Tommylee Lewis on 3rd-and-10 with 1:45 remaining in the 4th quarter.

[11] The fallout from the missed call was a factor in the NFL's decision to expand instant replay, making pass interference (including non-calls) reviewable.