Independiente del Valle defeated Colón by a 3–1 score to win their first Copa Sudamericana title.

[3] As champions, Independiente del Valle earned the right to play against the winners of the 2019 Copa Libertadores in the 2020 Recopa Sudamericana.

[4] On 14 August 2018, CONMEBOL decided that starting from the 2019 edition, the final would be played as a single match, and although it was originally stated that the final would be played in Lima, Peru at the Estadio Nacional,[5] on 9 May 2019 the confederation's Council decided to switch the venue to Estadio Defensores del Chaco in Asunción, Paraguay.

[7] Before the game, two bands identified with the finalist teams played on the field: Los Palmeras, for Colón, and La Vagancia, for Independiente.

If still tied after extra time, the penalty shoot-out would be used to determine the winner (Regulations Article 28).