The Huskies, led by Hall of Fame head coach Geno Auriemma in his 36th season at UConn, split their home games between Harry A. Gampel Pavilion and the XL Center and were members of the Big East Conference, which they joined for women's basketball that season.

1 ranked South Carolina; it was UConn freshman Paige Bueckers' third straight 30-point game.

UConn won the Big East tournament, winning all three of their games by over 30 points.

UConn then lost to Arizona in the Final Four and finished their campaign with a record of 28–2.

Bueckers, the team's leading scorer, won several awards at the end of the season, including the Naismith College Player of the Year.