Although they failed to match their 13–3 records from 2018 and 2019, the Saints defended their NFC South title for the fourth consecutive year following a Week 16 victory over the Minnesota Vikings.

After beating the San Francisco 49ers in Week 10, they won six straight games for the fourth consecutive season.

With a Week 13 win over the Atlanta Falcons, the Saints clinched a franchise record fourth consecutive playoff appearance.

During the Wildcard round against the Chicago Bears of the 2020–21 NFL playoffs, the Saints made history as one of the first two teams to air in a post-season football game on Nickelodeon, a primarily children-related network.

[3][4] Notes Front office Head coaches Offensive coaches Special teams coaches Strength and conditioning Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve The Saints' preseason schedule was announced on May 7, but was later cancelled due to the COVID-19 pandemic.

A potential game-winning 50-yard field goal by Chargers kicker Michael Badgley hit the upright instead, sending the game into overtime.

With 5:08 left in the overtime period, Wil Lutz kicked a 36-yard field goal to take a 30–27 lead.

But the night belonged to Marshon Lattimore, who stopped Chargers wide receiver Mike Williams on fourth down to seal the victory for New Orleans.

Bridgewater accidentally fell into the Saints sideline, but he reunited with his old friend Drew Brees who did the quarterback sneak earlier.

The Saints beat their rivals by 35 points, marking the second straight season to sweep them in the NFC South division.

This was an easy win due to the fact Drew Lock, Brett Rypien and Blake Bortles were all ineligible to play following Jeff Driskel testing positive for COVID-19 less than 24 hours before the game, which meant the Broncos named practice squad wide receiver Kendall Hinton, who played QB at Wake Forest, as starting quarterback for the game.

[95] In the end, Matt Ryan tried to throw a game-winning Hail Mary, but the Saints defense stepped up and made the ball drop to the ground.

With Brees making his return from injury, a late fourth-quarter rally was not enough as the Saints fell short to the defending Super Bowl champion Chiefs in Patrick Mahomes' first career game in New Orleans and the Mercedes-Benz Superdome.

Cameron Jordan became the first Saints player since Brodrick Bunkley (2012), Steve Gleason (2004), and Kyle Turley (2001) to be ejected from a game.

The Saints clinched their fourth consecutive division title as Alvin Kamara rushed for six touchdowns, tying a 91-year-old NFL record set by Hall of fame fullback Ernie Nevers of the Chicago Cardinals.

It also marked their first victory against Chicago in the playoffs, with the Bears having won the 1990 Wild Card game and the 2006 NFC Championship.