Santa Clara and the club's third consecutive season in the top flight of Portuguese football.

In addition to the domestic league, Santa Clara will participate in this season's edition of the Taça de Portugal, Taça da Liga, and the UEFA Europa Conference League.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: Liga Portugal The draw for the second qualifying round was held on 16 June 2021.