Karlslunde IF, Herlev IF, IF Lyseng, and Young Boys FD were promoted from the 2020–21 Denmark Series.
The top 6 teams will compete for 2 spots in the 2022–23 Danish 2nd Division.
Points and goals carried over in full from the regular season.
The bottom 6 teams will compete to avoid the 4 relegations spots to the 2022–23 Denmark Series.
Points and goals carried over in full from the regular season.