Domestically, Slavia finished the season 2nd in the league and reached the quarterfinal's of the Czech Cup.

In Europe, Slavia where knocked out of the Champions League at the Third qualifying round stage by Ferencváros, the Play-off round of the UEFA Europa League by Legia Warsaw and reached the quarterfinal of the UEFA Europa Conference League where they were defeated by Feyenoord.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: See results The draw for the third qualifying round was held on 19 July 2021.

[48] Kolář & Kovář both played in Slavia's 3-0 win against Fastav Zlín on 20 April 2022