The 2021 NCAA Division I Men's Lacrosse Championship was the 50th annual single-elimination tournament to determine the national championship for National Collegiate Athletic Association (NCAA) Division I men's college lacrosse.
Sixteen teams competed in the tournament based upon their performance during the regular season.
Virginia took control over an undefeated Maryland team in the Championship Game, at one point leading 16–11.
Maryland closed the gap in the fourth quarter scoring a goal with 10.8 seconds left to cut Virginia's lead to 17-16.
Terps had an open shot on goal to tie the game with two seconds left off a Luke Weirman face off win, but a save by Alex Rode won the title for UVA.