The 2022 BBVA Open Internacional de Valencia was a professional women's tennis tournament played on outdoor clay courts.

It was the second edition of the tournament and first ever as a WTA 125 event which is also part of the 2022 WTA 125 tournaments season.

It took place in Valencia, Spain between 6 and 12 June 2022.

[1] The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: