Iga Świątek defeated Maria Sakkari in the final, 6–4, 6–1 to win the women's singles tennis title at the 2022 Indian Wells Masters.

Paula Badosa was the defending champion,[2] but lost to Sakkari in the semifinals.

[3] The international governing bodies of tennis (WTA, ATP, ITF, Australian Open, French Open, Wimbledon, US Open) allowed players from Russia and Belarus to continue to participate in tennis events on tour and at the Grand Slams, but not under the name or flag of Russia or Belarus until further notice, due to the 2022 Russian invasion of Ukraine.

[5][6][7] Click on the seed number of a player to go to their draw section.

Seedings are based on WTA rankings as of February 28, 2022.