It was replaced by the Caribbean Cup, a regional cup tournament launched as a qualifying tournament to CONCACAF Champions League for teams from the Caribbean.

Among the 31 CFU member associations, four of them were classified as professional leagues and each may enter two teams in the CONCACAF Caribbean Club Championship.

The draw for the group stage was held on 3 February 2022, 11:00 EST (UTC−5), at the CONCACAF Headquarters in Miami, United States.

The two teams from the host association Dominican Republic, Cibao and Atlético Vega Real, were placed in Pot 1, the two teams from Haiti were placed in Pot 2, while the two teams from Jamaica were placed in Pot 3.

The semi-final matchups were: Winners qualified for 2022 CONCACAF League.