The 2022 European Open was a men's tennis tournament played on indoor hard courts.

It was the seventh edition of the European Open and part of the ATP Tour 250 series of the 2022 ATP Tour.

It took place at the Lotto Arena in Antwerp, Belgium, from 17 October until 23 October 2022.

[1] The following players received wildcards into the singles main draw: The following player was accepted directly into the main draw using a protected ranking: The following players received entry from the qualifying draw: The following players received entry as lucky losers: The following pairs received wildcards into the doubles main draw: The following pair received entry as alternates: