The 2022 Los Angeles FC season was the club's fifth season in Major League Soccer, the top tier of the American soccer pyramid.

Steve Cherundolo is the club's second head coach, joining on January 3, 2022.

[1] The club won their second Supporters' Shield and first MLS Cup title, hosting the final at Banc of California Stadium on November 5, 2022.

[2] Los Angeles FC did not participate in the 2022 MLS Superdraft as the club traded their draft picks in exchange for new players and General Allocation Money.

Win Draw Loss All matches are in Pacific time[38] Los Angeles FC will enter the Open Cup in the Third Round.