[2] In the middle of the season on August 31, 2021, the club fired Holly for cause and installed Mario Sanchez as interim head coach.

[3][4] On December 9, after the season concluded, the club announced the hiring of Kim Björkegren as the second permanent head coach of Racing Louisville.

[5] The 2021 NWSL Championship, originally planned to be played in Portland, Oregon, was moved by the league on October 13, 2022, to Racing Louisville's home ground of Lynn Family Stadium following player complaints regarding the artificial turf at Providence Park and the 9 a.m. local kickoff time required to meet television obligations.

Aside from free transfers, Racing traded Savannah McCaskill to Angel City FC,[12][13] Julia Ashley was sent to Houston Dash,[14][15] Yuki Nagasato was traded back to Chicago Red Stars,[14][16] and Kaleigh Riehl was selected by San Diego Wave FC in the 2022 NWSL Expansion Draft.

[18][14][24] Racing Louisville reloaded primarily through the 2022 NWSL Draft, bringing Jaelin Howell, Savannah DeMelo,[25] and Jordyn Bloomer into the squad.

Louisville acquired Jess McDonald through a trade with North Carolina Courage, signed 2021 draftees Kirsten Davis and Parker Goins, and signed free agents Hillary Beall, Taylor Malham, Julia Lester, Rebecca Holloway, Alex Chidiac, Satara Murray, and Thembi Kgatlana to pro contracts.

The club did not offer permanent contracts to its other National Team Replacement players — Hannah Adler, Isabella Beletic, and Allison Whitfield.