The 2022 Melbourne Summer Set 2 was one of two tournaments of the Melbourne Summer Set.

It was a WTA 250 tournament of the 2022 WTA Tour, and it was played on hardcourts.

[1] Amanda Anisimova won the women's singles title, her second career WTA title.

Bernarda Pera and Kateřina Siniaková won the women's doubles title; with the win, Pera earned her first career WTA title.

[2] *per team The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: The following pair received a wildcard into the doubles main draw: The following pair received entry into the doubles main draw using a protected ranking: The following pair received entry into the doubles main draw as an alternate: